Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Eshan Kalyanikar is a health journalist with Times of India, Mumbai.

Lorundrostat, a selective aldosterone synthase inhibitor, significantly reduced 24-hour systolic blood pressure in individuals with uncontrolled and treatment-resistant hypertension, according to ...

Aldosterone dysregulation contributes to hypertension ... shown were calculated with the use of the serum creatinine level. Lipid disorders included dyslipidemia, hypercholesterolemia ...

and other diseases driven by dysregulated aldosterone, today announced that the New England Journal of Medicine (NEJM) published the detailed results from the Company’s pivotal Phase 2 Advance ...

TUESDAY, May 6, 2025 (HealthDay News) — A test commonly used to confirm a condition linked to high blood pressure is often ...

"Excess levels of aldosterone are associated with hypertension and several cardiorenal diseases, including chronic kidney disease and coronary artery disease and being able to effectively reduce ...

In the absence of contraindications, an aldosterone antagonist should be offered to patients with NYHA class III or IV heart failure and to patients after an MI with left ventricular dysfunction.