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Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types
Previous studies show that DNMT inhibitors cause cancer cells to behave as if infected by a virus, which makes the cells more susceptible to attack by one's own immune system. In their new study ...
Nature13y
Molecular basis for the actions of Hsp90 inhibitors and cancer therapy
The Hsp90 inhibitor disrupts the Dnmt-1/Hsp90 association and upregulates pRB expression. In this review, the Hsp90 inhibitors that show promise for cancer therapy are summarized. The integral ...