Scientists explored selectively blocking the CYP3A4 protein responsible for breaking down large swaths of approved drugs, providing a way to improve drug efficacy.

However, efforts to develop small-molecule drugs to target these proteins have largely ... researchers placed special landing spots for the cJun protein inside an important gene in lab-grown ...

UM researchers have developed a deep learning model to predict compound protein interactions. GraphBAN is an inductive ...

Researchers have identified a previously unknown bacterial protein, the structure of which is being used in the design of protein nanoparticles for the targeted delivery of anticancer drugs to tumors.

The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

A team of scientists from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has identified ...

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows ...

Scientists at the University of Iowa have made an exciting discovery that could lead to new cancer-fighting drugs. They found ...

Certara accelerates medicines using biosimulation software, technology, and services to transform traditional drug discovery and development. Its clients include more than 2,400 biopharmaceutical ...