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Avacopan has been shown to work well in a real-world setting in a much broader group of people with vasculitis than was studied in the phase 3 trial that led to its approval.
Long-term use of propylthiouracil (PTU) may precipitate antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV ... (286.30 AU/mL), confirming PTU-induced AAV.
The FDA has granted Orphan Drug designation to NS-229 for the treatment of eosinophilic granulomatosis with polyangiitis.
There were 50 individuals in the control group, with 12 having received a diagnosis associated with other connective tissue diseases and 7 suspected of demonstrating drug-induced symptoms.