In 1975, Barbara Pearse identified the protein that coated the endocytic vesicles. She named the protein clathrin for its ability to form lattice-like structures (Pearse 1976). By sequencing ...

Eps15 immunoprecipitates with a number of endocytic proteins ... They found that, at resting synapses, Eps15 was associated with vesicles in the presynaptic terminal but was virtually excluded ...

Homotypic fusion between late endosomes. (A) Time-lapse imaging of endocytic vesicles in VE cells. (B) By labeling of VE ...

The maintenance of synaptic transmission requires that these vesicles be retrieved by a reverse process, i.e. endocytosis. How is this endocytic activity and subsequent formation of fusion-competent ...

Our lab is interested in the molecular mechanisms of cargo sorting along the endocytic pathway with particular emphasis on the regulation of the clathrin coated vesicle cycle by rab5 and reversible ...