Figure 6: An interaction-competent mutant of ARNO rescues MTC cells from the inhibitory effect of a2N on receptor-mediated protein endocytosis. Having demonstrated that endosomal acidification is ...

thus questioning its use as a specific inhibitor of cargo recognition by the AP-2 adaptor complex via tyrosine motif-based endocytosis signals. Furthermore, we show that cytoplasm acidification ...

This article provides an introduction to dynamin and endocytosis and lists the inhibitors that are relevant to research. Dynamin is an important GTPase enzyme that takes part in different ...

Theories about endocytosis called into question Date: February 19, 2015 Source: Université de Genève Summary: There is no unequivocal explanation behind endocytosis. Two hypotheses prevail for ...

Endocytosis and degradation of the membrane receptors in the lysosome controls the activation of intracellular signaling pathways, but the mechanisms that control the endocytosis itself are largely ...

The new study in Cell Reports finds that in astrocytes, which are the most common non-neuron cell in the brain, the variant hampers the process of endocytosis, which is a major way that cells ...