This had puzzled the researchers, since it did not fit a simple model in which epithelial tissues behave like linear springs. In such a model, the extension obeys Hooke’s law and is proportional to ...

Tissues change their shape in three dimensions ... could be a technique to explain animal development. Using a physical model, we showed that collective, programmed cell behaviors are sufficient ...

Professor Dong Sung Kim's team addressed this limitation by developing an epithelial tissue model composed solely of human epithelial cells and extracellular matrix (ECM). By combining this model ...