Thus, the C-H bonds make it difficult to modify ketones and esters. But now chemists at Scripps Research have uncovered the key to unlocking these molecules' untapped potential.

DNA and RNA are composed of nucleotides that are linked to one another in a chain by chemical bonds, called ester bonds, between the sugar base of one nucleotide and the phosphate group of the ...

Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...