This research helps us to understand the evolution of bacterial resistance to phage infection, and demonstrates that—under the right conditions—phages can overcome this resistance. Bacteria ...

“The field of phage biology has seen an explosion over the last decade because more researchers are realizing the significance of phages in ecology, evolution, and biotechnology,” said Ido ...

Esvelt’s system, dubbed phage-assisted continuous evolution, or PACE, allowed scientists to hit fast forward, evolving a protein with a specific function in as little as a week. 1 The PACE system has ...

Day1: Phage Discovery & Genomics allows you to explore the hidden world that exists all around you. Isolate, characterize and name your newly discovered phage. Sequence the DNA of your phage and ...

Phage biology is the scientific discipline concerned ... This includes the distribution, biochemistry, physiology, cell biology, ecology, evolution and applications of phages.

In this way, scientists could retain only positive clones and immediately use their selected phage to generate more phages. This made screening higher throughput, as researchers could screen thousands ...

either because in past attempts a single phage did not kill all the targeted bacteria or because the bacteria evolved to be resistant, similar to the evolution of antibiotic resistance," adds Dr ...

Treatment with phages or antibiotics individually can lead to resistance evolution. An evolutionarily informed phage-antibiotic combination however, can reduce resistance evolution. Created with ...

However, it is not well understood if and how antibiotics, when co-administered with phage, alter bacterial evolution of resistance. To determine this, I am evolving bacteria under a wide range of ...