Esvelt’s system, dubbed phage-assisted continuous evolution, or PACE, allowed scientists to hit fast forward, evolving a protein with a specific function in as little as a week. 1 The PACE system has ...
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The phage wars: multiple viruses block each other from infecting cells“The field of phage biology has seen an explosion over the last decade because more researchers are realizing the ...
Results show that phage selection produces an evolutionary trade-off in MDR P. aeruginosa, whereby the evolution of bacterial resistance to phage attack changes the efflux pump mechanism, causing ...
Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by approximately a decade. In this ...
Phage therapy has recently garnered significant attention as an alternative or adjunctive approach to conventional antibiotic treatments, especially against ...
Scientists insert variable DNA sequences coding for their proteins of interest into plasmids that carry a phage coat protein gene, an antibiotic resistance gene, and a packaging signal. Then they ...
However, it is not well understood if and how antibiotics, when co-administered with phage, alter bacterial evolution of resistance. To determine this, I am evolving bacteria under a wide range of ...
Because phages exert pressure on the bacteria they infect and some phage genomes encode virulence factors and toxins, a role for specific phages or communities of phages in human health seems ...
Because phages exert pressure on the bacteria they infect and some phage genomes encode virulence factors and toxins, a role for specific phages or communities of phages in human health seems ...
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