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The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in ...
Researchers show that glycoRNAs, uncovered by the lab of Nobel Laureate, Carolyn Bertozzi, can be used to fight cancer.
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Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular ...
Extending this discovery recently in Cell, Flynn and colleagues showed that glycoRNAs form highly organized clusters with RNA-binding proteins on the cell surface. These clusters appear to ...
The labs of Ryan Flynn at Boston Children’s Hospital and Konstantinos Tzelepis at the Cambridge Stem Cell Institute have found a readily druggable target on the surface of acute myeloid leukemia (AML) ...
The structure of the PP7 bacteriophage coat protein revealed a mode of RNA binding that is distinct from that of the well-characterized MS2 coat protein, suggesting new orthogonal systems for RNA ...
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