At ARVO 2025, in Salt Lake City, Utah, Steven Barnes, PhD, talked about his research on the OPA1 mutation in retinal ganglion cells' effect on the cell's electrical function.

Technological advances have enabled the observation of a large number of retinal ganglion cells (RGCs ... the retina and promote the survival and function of RGCs post-injury.

A ganglion is a cluster of nerve cells found in the peripheral nervous ... thalamus and brainstem and is associated with several key functions including motor control, emotions, cognition and ...

"Ganglion cells that show an increased activity pattern ... do these properties remain stable even if the cells lose their original function—for example, if the retina's photosensors no longer ...

In follow-up studies using CRISPR, his lab is looking to find other genes that are important for ganglion cell survival and function. "We hope that these cells can eventually lead to new ...

Retinal Ganglion Cells (RGCs) are specialized neurons that ... allowing it to perform different visual system functions. RGCs are the final output neurons of the retina. They are responsible ...

The main function of the eyes is enabling people ... Thin retinal fibers called ganglion cells carry light information from the retina to the brain. The ganglion cells leave the eye at a point ...

"We discovered that abnormal tau proteins accumulate in retinal ganglion cells, which are key nerve ... to the brain and a decline in cognitive function, Koronyo-Hamaoui said.

Researchers are investigating the mechanisms and identifying new areas of the brain that can benefit patients when stimulated ...