Researchers hope the AI tool will aid in the development of cell-specific gene therapies to treat diseases such as cancer.
Activator proteins bind to regulatory sites on DNA nearby to promoter regions that act as on/off switches. This binding facilitates RNA polymerase activity and transcription of nearby genes.
Being able to predict which genes are turned on, off, up or down in different cells could help determine the cell of origin for a disease. A model that makes accurate predictions about gene ...