The chromatoid body, a unique cloud-like structure of male germ cells, moves dynamically in the cytoplasm of haploid spermatids, but its function has remained elusive for decades. Recent findings ...

This sets up a new structure that cements the cell's future fate as a sperm cell. The companion paper shows that well before the germ cells enter meiosis, CTCF and other proteins bookmark ...

These primordial germ cells are initially bipotent (able to ... This sets up a new structure that cements the cell’s future fate as a sperm cell. The companion paper, “ZBTB16/PLZF regulates ...

The micronucleus is the germ ... the cell. When Blackburn carried out sequencing experiments for the ribosomal DNA minichromosome, she was surprised to find that the telomeres of this structure ...

A critical early cell fate decision is whether to develop as germline (reproductive) or soma (non-reproductive). My research focuses on assessing how the highly conserved DREAM transcriptional ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop into sperm and eggs, are formed. In six to 10 weeks after fertilization, PGCs differentiate into pro ...

This sets up a new structure that cements the cell’s future fate as a sperm cell. The companion paper shows that well before the germ cells enter meiosis, CTCF and other proteins bookmark ...