Deletions and duplications of single-base pairs typically arise during homologous recombination and cause diseases. But what happens when a mutation occurs over multiple genes?

Next, the investigators queried the identity of the pulled-down DNA by PCR, using primer pairs to amplify short sequences spanning the entire β-globin gene region. The DNA that was pulled down by ...

The team attempted to amplify the same fragment that Mullis targeted—a 110 base pair segment from the human β-globin gene. At first, they could not determine if they achieved specific target ...

Thalassemia is classified into two main types based on which part of the haemoglobin molecule is affected: Alpha Thalassemia Cause: Mutations in the genes responsible for producing alpha-globin ...