Discover how the brain's most abundant neurotransmitter, glutamate, is revolutionizing psychiatry and offering new hope for ...

Silent synapses are dormant neural connections that hold untapped brain potential. Discover how ketamine, exercise, and other ...

For this purpose, the researchers imaged individual synapses of neurons in the mouse visual cortex while simultaneously recording their spontaneous electrical activity. The glutamate indicator signal ...

Unless otherwise stated, the mechanisms pertain to glutamate or GABA synapses onto hippocampal CA1 pyramidal cells, a preparation that has been used for almost all trafficking studies. Hippocampal ...

the most numerous synapses in our brain, the presynaptic nerve ending contains several tens to a few hundreds of synaptic vesicles filled with the neurotransmitter glutamate. Each time a terminal ...

Amino acid balance could play a role in SMA, as a study showed acids able to influence nervous system function were ...

a study that demonstrates the crucial role of one of the receptors for the neurotransmitter glutamate in the functioning of ...

Most excitatory synapses use the neurotransmitter L-glutamate, which activates specific receptor channels in the postsynaptic membrane. Molecularly and functionally different glutamate-activated ...

Schematic of synapses with and without Noelins. On the left, Noelin proteins anchor the AMPA glutamate receptor and other associated proteins to the synapse and other regions of the nerve cell.

So far, we have identified several novel features related to functions and regulation of AMPA and kainate-type glutamate receptors at the developing synapses. Our current research aims to understand ...

We are also interested in glial cells because of their critical role in glutamate neurotransmission, synaptic plasticity, and neuroenergetics. The pathophysiologic effects of trauma and chronic stress ...