Innovative molecular therapies target and disrupt uncontrollable growth of cancer cells
Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the ...
HDAC Inhibitor Clinical Trials and Studies: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies by DelveInsight
DelveInsight’s, “HDAC Inhibitor Pipeline Insight” report provides comprehensive insights about 40+ companies and 50+ pipeline ...
Hosted on MSN11mon
Surprising study suggests brewery fumes could delay cancer and Alzheimer’s
The team found that diacetyl can act as an inhibitor of histone deacetylase, or HDAC and enzymes. HDAC inhibitors, conserved in plants and animals, are used as anti-cancer drugs and treat ...
Nature6y
Celgene acquires Gloucester Pharmaceuticals, gaining approved HDAC inhibitor
Furthermore, such enzymes can have other substrates, leading to effects that are not related to their action on chromatin.” Romidepsin is the second HDAC inhibitor to be approved for the ...
Medindia5y
New Study Makes Breakthrough Discovery into the Regulation of a Key Cancer Drug Target
In addition, we have shown that two MTA1 molecules come together to recruit two HDAC enzymes, and we suggest that MTA1 is critical for recruiting HDAC1 to DNA." Professor Schwabe also emphasised ...