Liver epithelial cell lines are considered the cell culture counterpart of liver stem/progenitor cells (for a detailed review, see Grisham and Thorgeirsson [10]). Several laboratories, including ...

HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

Mesenchymal stem cells (MSCs) once looked likely to avoid such attacks. However, recent studies have shown that some MSCs are more immunogenic than others. Liver-derived MSCs, such as Promethera ...

An Osaka Metropolitan University-led study demonstrated that Cdc42 (cell division cycle 42) plays a crucial role in the formation and maintenance of the morphological characteristics of quiescent ...

Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study found that placenta-derived IL1 under ...

Hepatic stellate cells control liver function and regeneration Date: March 12, 2025 Source: German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) Summary: Until now, doctors knew ...

In healthy liver, quiescent hepatic stellate cells (HSCs ... We have developed a protocol to direct the differentiation of human induced pluripotent stem cells (iPSC) to HSCs. The final HSC–like ...

Among them are: Infection Stem cell failure Hepatic veno-occlusive disease (VOD), in which blood vessels in your liver get blocked Posttransplant lymphoproliferative disorder (PTLD), out-of ...

Liver cells. Brain cells ... at fertility clinics and establishing the world's first human embryonic stem cell line, he and other scientists got a lot more than they bargained for.

Due to the development of research methods since the early 21st century, it has been possible to demonstrate the existence of stem cells in nearly all organs. The development has led to the discovery ...

researchers in China say they have successfully treated a patient with late-stage type 2 diabetes using stem cell-derived islet cells transplanted into the liver. In 2021, The New York Times ...