Making a PCB is very simple ... same circuit is the reason that forces many away from using protoboard. After making your first circuit board, you might not point-to-point wire anything again!
Normally, you have a choice with PCB prototypes ... edges around the board with fiducials, you could make a jig that would hold the board in a very precise position using the holes in the carrier ...
NVIDIA details its beast quad-slot, triple-fan RTX 40 or TITAN prototype with an interesting rotated PCB as the GeForce RTX 5090 preps for launch.
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