The prevalence of obesity is steadily rising and has huge health and financial implications for society. Weight gain is due to an imbalance between dietary intake and energy expenditure and research ...

The hypothalamus is a multinucleated structure and internuclear connections have been extensively investigated. However, the microcircuits inmost hypothalamic nuclei have been less examined. To fill ...

The hypothalamus integrates neurohormonal signaling from gut and adipose tissue. Specific hypothalamic nuclei, including the dorsomedial nucleus (DMN), paraventricular nucleus (PVN) and ventromedial ...

Exposure to higher levels of light can help people feel more awake and increase cognitive performance, probably by influencing the activity of parts of a brain region called the hypothalamus, ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

Breakthrough MRI scans reveal hidden hypothalamic changes in young women, shedding light on the biological roots of anorexia and obesity, and paving the way for targeted treatments. Study: Unraveling ...

What if your brain couldn’t register the meals you ate or, despite restricting food intake, you continued to gain weight? For people with hypothalamic obesity (HO), there are no approved treatment ...