Indomethacin, ibuprofen, and gentamicin cause significant change in glomerular and tubular structure in the neonatal rat model. Gentamicin is frequently administered at the same time as ...

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a type of tocolytic. NSAIDs include ibuprofen (Motrin) and indomethacin (Indocin). Indomethacin is the most frequently used NSAID for preterm labor.

The prophylactic administration of indomethacin reduces the frequency of patent ductus arteriosus and severe intraventricular hemorrhage in very-low-birth-weight infants (those with birth weights ...

Eligible patients were randomized to receive two 50-mg indomethacin suppositories or two matching placebo suppositories immediately after ERCP. The authors say the results of the trial have ...

Indomethacin is the conventional treatment for patent ductus arteriosus in preterm infants. However, its use is associated with various side effects. In a prospective study, we compared ibuprofen ...