The UVA researchers have shown that a specific immune molecule, interferon gamma, seems to be critical for social behavior and that a variety of creatures, such as flies, zebrafish, mice and rats ...

The starting point for the study was an observation made by Blankenstein and his team a few years ago: "We noticed that the molecular structure of the cytokine interferon-gamma differs greatly ...

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways ...

The interferon-induced GTPase GVIN1 prevents bacteria from spreading among cells by coating them and rendering them immobile.

[Laboratory of Molecular Metabolism at The Rockefeller ... Their study demonstrates how interferon gamma uses four amino acids to bind to the extracellular matrix of connective tissue, which ...

Pro-inflammatory signaling molecules in MS cause problems with the growth and development of myelin-making cells in the brain ...

postdoctoral fellow Anthony Filiano led a study that used genetic modifications in mice to block a molecule — known as interferon gamma — normally found in the immune system. Blocking it ...

along with significant production of the proinflammatory cytokine interferon-gamma, or IFNγ. Now in a study published in Acta Neuropathologica Communications, Harms and colleagues used the mouse model ...

Interferon-gamma is a major driver of pathology in HLH ... Besides EI‑001, Elixiron has an orally-administered, small molecule inhibitor of the colony stimulating factor‑1 receptor (CSF ...

By Day 10, early in the flu infection, nearly 40 percent of the Tfh cells were producing interferon-gamma, or INF-γ; but that frequency dropped sharply thereafter. The researchers asked whether the ...

small molecule interferon-α receptor (IFNAR) agonist designed to selectively activate the interferon-α pathway within the liver and offer the convenience of oral dosing. Interferon-α is a ...