“PADI4 regulates transcription [of genes involved in brain repair] and inflammation. Remarkably, expressing PADI4 in mice limited the extent of tissue damage and inflammation after ischemic ...

Although the adult brain can self-repair ... "We investigated the changes in lipid metabolite production in mice after ischemic stroke. Interestingly, the levels of a specific fatty acid called ...

Cerebral edema contributes significantly to morbidity and death associated with many common neurological disorders. However, current treatment options are limited to hyperosmolar agents and ...

Ischemic stroke exacts a heavy toll in death and disability worldwide. After ischemic stroke, the accumulation of ...

A new clotbusting drug tested on mice has been ... "When someone has an acute ischemic stroke, doctors need to quickly remove the clot blocking cerebral arteries in the brain.

Traumatic brain injury (TBI ... can reduce lesion size and reverse motor deficits in TBI and ischemic stroke mice, demonstrating that LDIR may be a promising therapeutic strategy for TBI and ...

A study shows how a class of drugs, HDACi (histone deacetylase inhibitors), protects neurons and limits brain damage ...

“Although generating new neurons in the ischemic injured brain would be an ideal approach ... The scientists caused a stroke-like injury in mice by temporarily blocking the right middle cerebral ...

In addition, after performing transient middle cerebral artery occlusion (tMCAO) surgery to induce ischemic stroke in mice, the research ... function and treating brain I/R injury," He adds ...

Ischemic stroke is a fatal condition caused by an arterial embolism ... Fibroblast growth factor 21 (FGF21) is likely the only member of the FGF family that may cross the blood-brain barrier. Among ...

Traumatic brain injury (TBI ... can reduce lesion size and reverse motor deficits in TBI and ischemic stroke mice, demonstrating that LDIR may be a promising therapeutic strategy for TBI and ...