Like a lock and key, ketamine binds to the brain via N-methyl-D-aspartate (NMDA) receptors. NMDA receptors are all over the brain and are essential in maintaining consciousness. The study came ...

The interplay of opiate and NMDA glutamate receptors may contribute to psychosis, cognitive function, alcoholism, and substance dependence. Ketamine and ethanol block the NMDA glutamate receptor.

EXCLUSIVE: Former adult actress Emily Willis has been left 'permanently disabled' after checking into rehab for her ketamine ...

Now ketamine, a glutamatergic NMDA receptor antagonist, may provide a mechanism that could link these pathways. Figure 1: A schematic of how ketamine may lead to an overall excitation in the cortex.

led researchers to explore drugs that affected glutamate—and specifically within the N-methyl-D-aspartate (NMDA) receptor class—with ketamine being a prime focus (Berman et al., 2000).

“This is the largest study to date evaluating the antidepressant effects of an NMDA receptor antagonist,” first author Gerard Sanacora, a professor of psychiatry at Yale University, told Everyday ...

Johnson & Johnson has announced the FDA’s approval of a first-of-its-kind, esketamine nasal spray called Spravato for the ...

Why We Need Fast-Acting Anxiety Relief Now More Than Ever Anxiety isn’t just feeling nervous before a big event—it can be relentless, overwhelming, and even debilitating. Traditional treatments like ...

CIII allows people who have tried at least two oral antidepressants to use the spray on its own – without the need for more ...

In a study published in Cell, a research team led by Zhu Shujia from the Center for Excellence in Brain Science and ...

One main class of these drugs, which includes propofol and the ether-derivative sevoflurane, work primarily by increasing the activity of inhibitory GABAA receptors, while a second class that includes ...