Mayo Clinic's Molecular Neurotherapeutics Lab cloned a neuron-specific tau kinase from the human brain tissue cDNA library ...

a) Ribbon diagram of human p110γ (protein data bank [PDB] code ... For example, we remain unsure about whether the addition of mTOR inhibitory activity to a class I PI3 kinase inhibitor activity is ...

This could promote enzymatic activity in conjunction with ... The figure is a schematic diagram depicting polo-like kinase 1 (PLK1) as a regulator of several stages during mitotic progression.

MEK ± BRAF inhibitors demonstrated greater clinical activity in class 2 compared with class 3 BRAF ... and that these classes exhibit distinct sensitivities to mitogen-activated protein kinase ...

On the basis of the substantial activity of the inhibitor in patients in the chronic phase, we evaluated STI571 (formerly known as CGP 57148B), a specific inhibitor of the BCR-ABL tyrosine kinase ...

This modification regulates the activity, localization, and function of proteins, ultimately influencing various cellular activities. Disruption in these kinase-substrate interactions is often ...