Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.

Creatine kinase is an enzyme that’s responsible for healthy muscle function. When muscles break down, they release CK, elevating the protein levels in your blood. These levels can be measured ...

This modification regulates the activity, localization, and function of proteins, ultimately influencing various cellular ...

As of 2024, over 80 small-molecule protein kinase inhibitors have received FDA approval, most of which function by inhibiting ATP binding to the target kinase 1,2 . However, the effectiveness of these ...

Mammalian AMP-activated protein kinase (AMPK) was discovered as a protein ... recent results indicate that the AMPK system is also important in functions that go beyond the regulation of energy ...

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge.

Scientists at deCODE genetics/Amgen have identified associations between bipolar disorder and rare loss-of-function variants ...