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Kinase is an enzyme that phosphorylates proteins. Phosphatase is an enzyme that dephosphorylates proteins, effectively undoing the action of kinase. Protein surfaces are designed for interaction.
Phage T4 polynucleotide kinase/phosphatase (Pnkp) and RNA ligase 1 (Rnl1) are prototypal RNA healing and sealing enzymes. They function in vivo to repair a break in E. coli tRNA Lys triggered by phage ...
MK-STYX is a novel protein included in the dual specificity mitogen-activated protein kinase phosphatase class that lacks the essential nucleophilic cysteine required for phosphatase activity.
The phosphoinositide 3-kinase (PI3K) pathway is a crucial signal ... P 3), and the tumor suppressor PTEN (phosphatase and tensin homologue), a lipid phosphatase that dephosphorylates PtdIns ...
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