To establish a diagnosis of spindle cell leiomyosarcoma a combination of two of three of the following features are needed: tumor cells necrosis, marked moderate to severe cytologic atypia and/or ...

A diagnosis of stage IIIB leiomyosarcoma of the rectus was made. No adjuvant therapy was administered. Fig 1. Histology of the excised abdominal wall tumor shows fascicles of atypical spindle cells ...

Uterine leiomyosarcoma is a rare and aggressive cancer that occurs in the uterus. Individuals usually require a hysterectomy. Treatments can also include chemotherapy or radiotherapy ...

In 1 case hemorrhagic tumor necrosis was noted ... Because the diagnosis of a soft-tissue tumor, such as a leiomyosarcoma, is often not evident from the clinical examination, a tissue-biopsy ...

Mid-2024, Intensity Therapeutics will start Phase 3 and Phase 2/3 trials respectively in soft tissue sarcoma and triple-negative breast cancer. INT230-6 has shown up to 95% tumor necrosis ...

Uterine leiomyosarcoma is a rare form of cancer. The earlier uterine leiomyosarcoma is diagnosed, the better the outlook. Uterine leiomyosarcoma accounts for 2–5% of all uterine cancers.

If you’ve been diagnosed with leiomyosarcoma, a rare form of cancer that starts in smooth muscle tissues, it’s important to find a doctor and treatment team who have experience treating ...

Make sure you know what you can expect during the trial, including how long it will last. Sometimes clinical trials end early or abruptly, and you may or may not have an option to continue to take ...

Following the tragic passing of inspirational cancer campaigner Vicky Phelan, aged 42, awareness is more crucial than ever for this rare and aggressive form of uterine cancer. Uterine ...

More information: Patricia Pautier et al, Doxorubicin–Trabectedin with Trabectedin Maintenance in Leiomyosarcoma, New England Journal of Medicine (2024). DOI: 10.1056/NEJMoa2403394 ...

In 2021, further testing revealed she had stage 4 uterine leiomyosarcoma, a rare cancer of the smooth muscles in the uterus. “I saw a junior doctor… (who) didn’t even tell me I had cancer at ...