In humans, many leptin deficiency syndromes are responsive to leptin replacement therapy. As leptin is involved in numerous pathways, the effects of too little leptin are widespread (including ...

This includes congenital leptin deficiency, a condition that causes mutations in the leptin gene. People with these ...

This experience tells us that weight loss is not all about the simple equation of calories in vs. calories out. Obesity isn’t ...

In obesity, while hyperleptinemia highly correlates with excess fat mass, the status of gastric leptin remains unknown. Here, we investigated the expression of leptin in stomach biopsies of obese ...

Satizabal is lead author of the study titled, "Leptin bioavailability and markers of brain atrophy and vascular injury in the middle age," published Aug. 12 in Alzheimer's & Dementia: The Journal ...

Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by a near-total absence of ...