The result suggests that the protein made by the gene, known as Nwd1, and other molecules it interacts with could be ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers from the German Cancer Research ...

HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

Researchers from Columbia University and the German Cancer Center have found that stellate cells—star-shaped liver cells long known as the main perpetrators of liver fibrosis—have a commanding ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns. It is prevalent in 30% of ...

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.

Mesenchymal stem cells (MSCs) once looked likely to avoid such attacks. However, recent studies have shown that some MSCs are more immunogenic than others. Liver-derived MSCs, such as Promethera ...

The researchers identified several liver bile acids associated ... LCA impaired T cell function by causing endoplasmic reticulum stress, wherein cells can no longer properly fold and modify ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their ...

Hepatic stellate cells control liver function and regeneration Date: March 12, 2025 Source: German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) Summary: Until now, doctors knew ...