In a mouse corneal angiogenesis assay, FGF-2 stimulates both lymphangiogenesis and angiogenesis. FGF-2 upregulates VEGF-C expression in vascular endothelial and perivascular cells. Anti-VEGFR-3 ...

Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from ...

We do biomedical research in vascular biology with a focus on lymphangiogenesis and the VEGF family of growth factors. Blood and lymphatic vessels play important roles in almost all major human ...

Lymphangiogenesis, i.e., the development of lymphatic vessels, is generally associated with a poor prognosis, as it favors the spread of metastases to other organs. By studying the cells that make ...

Lymphangiogenesis, i.e. the development of lymphatic vessels, is generally associated with a poor prognosis, as it favours the spread of metastases to other organs. By studying the cells that make ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but effective treatments are lacking. Cardiac lymphatics play a crucial role in ...