MSA is considered a rare disease affecting potentially 15,000 to 50,000 people in the United States. Symptoms tend to rapidly progress over 5-10 years with loss of function and increasing disability.

Clinically Meaningful Benefit Observed at Both ATH434 Doses Studied –– Achieved Statistical Significance with Up to 48% Slowing of Clinical ...

In addition to Alzheimer's disease, posterior cortical atrophy may occur with Lewy body dementia and some other progressive ...

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Is a very rare form of Spinal Muscular Atrophy caused by mutations in the gene. Symptoms appear during infancy, between ages 6 weeks and 6 months. Children with SMARD1 suddenly may be unable to ...

Vulvovaginal atrophy is a frequently neglected symptom of menopause. While an estimated 10–40% of women are affected by the progressive symptoms of vaginal dryness, irritation, itching ...

MSA is divided into MSA-C (cerebellar type) which has more symptoms of ataxia (incoordination) and MSA-P (parkinsonian type) which has more parkinsonian symptoms but is relatively unresponsive to the ...

Problems with chemical messengers like dopamine were tied to posture issues in SMA in a mouse study, but levodopa therapy may ease symptoms.

Direct application of local estrogen to the vulvar vestibule, with the consideration of adding a local androgen as well, is important to adequately treat symptoms of vulvovaginal atrophy.