Patients with LORA and CLD at baseline had lower rates of treatment response and a higher risk for SAEs over 5 years, compared against those without CLD.

Methotrexate (MTX) has been used for rheumatoid arthritis (RA) treatment since 1980. It is the most common effective disease-modifying antirheumatic drug (DMARD) for RA, and is considered to be ...

Methotrexate or MTX, a common cancer drug, works by interfering with cells' ability to use folic acid, essential for making DNA and RNA. By blocking a certain enzyme, MTX thwarts replication of ...

p < 0.05. **p < 0.001 compared with no Tx group. Fum-NP: Fumagillin-nanoparticle; MTX: Methotrexate; Tx: Treatment. *p < 0.01. **p < 0.001 compared with no Tx group. Fum-NP: Fumagillin ...

Due to its ability to penetrate the blood-brain barrier, MTX is one of the most common chemotherapeutic agents used worldwide ...

Methotrexate sodium 2.5mg; scored tabs. Be fully familiar with this drug's toxicity before use. Obtain baseline and monitor CBCs for myelosuppression, and hepatic, renal and pulmonary function ...

Methotrexate (MTX), an older oral DMARD, remains the gold standard of treatment and is included in most combination therapy strategies. However, traditional DMARDs have a slow onset of action and ...

Pegloticase therapy for uncontrolled gout does not appear to significantly increase the risk for cardiovascular (CV) or thromboembolic (TE) events, despite the potential for increased gout flares ...