Mechanistic studies showed that Lrrk2 promotes macrophage polarization toward the M1 phenotype by enhancing STAT1 phosphorylation in response to IFN-γ signaling. This function is dependent on the ...

Evaluation of abiraterone acetate post-docetaxel in the Belgian compassionate use program. High neutrophil to lymphocyte ratio (NLR) persistence during enzalutamide to predict poor clinical outcome in ...

High-grade gliomas (HGGs) and immunotherapeutic early-phase clinical trials (ieCTs): A single-center experience. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I. This abstract ...

The polarization of macrophages is crucial in modulating the tumor microenvironment and impacting cancer development. Long ...