The skin condition is notoriously tough to treat, but these topical treatments can work alone or complement in-office ...

[19] This may be the other mechanism of action of Silymarin in the treatment of melasma. Silymarin inhibited l-DOPA oxidation activity of tyrosinase, the rate-limiting melanogenic enzyme ...

it is advisable to switch to a milder cream containing azelaic acid, kojic acid, and glycolic acid for maintenance and to prevent recurrence, the doctor advised. Melasma isn’t life-threatening ...

For those expecting mamas or mamas who just gave birth, we’re sure one pesky skin problem you never considered before was melasma ... You apply this cream both day and night.