News Medical on MSN1d
CD2AP and Alzheimer’s disease: A key regulator of neurodegeneration and potential therapeutic target
A comprehensive Thought Leaders Invited Review in Brain Medicine highlights the crucial role of CD2-associated protein (CD2AP ...
ALZFORUM7d
After Immunotherapy, Amyloid Clearance Comes Down to Microglial Moods
Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...
Hosted on MSN2mon
New approach enables a closer look at microglial organelles
A phagosome can then fuse with other organelles that break down its contents. Microglial phagosomes play important roles in brain development, brain function and a plethora of brain diseases ...
Hosted on MSN3mon
Microglial responses to hypernatremia: New insights into brain health
However, when the brain is subjected to hyperosmotic stress—a condition characterized by elevated extracellular sodium levels, the microglial response can become exaggerated, leading to ...
Scientific Research Publishing7d
The Role of Microglia in Pediatric Neurological Disorders ()
Microglia, Pediatric Neurology, Autism Spectrum Disorder, Epilepsy, Neuroinflammation, Neurodevelopment Kaur, H. (2025) The Role of Microglia in Pediatric Neurological Disorders. Neuroscience and ...
Nature3mon
Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment
Up to a quarter of the regional microglial population is donor-derived by four months after transplantation. Microglial engraftment is enhanced by neuropathology, and gene-modified myeloid cells ...