When calculated from synchronous measurements of sodium and potassium in serum as well as in urine in a fasting state, the SUSPPUP ratio reflects the mineralocorticoid excess and was proposed as a ...

The autosomal recessive syndrome of apparent mineralocorticoid excess causes severe hypertension through mutations in the 11β-HSD-2 gene (Figure 3B), which render the enzyme ineffective.

In addition to the classical form of primary aldosteronism, renin suppression is also found in apparent mineralocorticoid excess, adrenal biosynthetic defects, glucocorticoid excess, licorice ...

and in rare cases the syndrome of apparent mineralocorticoid excess (AME). A genetic mutation can result in AME although it can be acquired with chronic ingestion of glycyrrhizic acid, an ...

In chronic kidney disease (CKD), kidney function is impaired over time, and the resultant build-up of excess fluid and ... an association between the use of mineralocorticoid receptor antagonists ...

In patients with metabolic alkalosis and high urine chloride, assessment of effective arterial blood volume and blood pressure may distinguish those with metabolic alkalosis caused by a diuretic from ...

We think the mineralocorticoid receptor may explain ... much as obesity, particularly excess weight around the middle, is considered a metabolic disease. Increased fat in the bone marrow is ...

“The differential extent of mineralocorticoid excess provided by [abiraterone plus prednisone vs darolutamide] may explain this observation,” according to Dr Canfield and colleagues. They ...