A collaborative study from the University of Cologne has uncovered how a key mitochondrial protein, AIFM1 (Apoptosis-Inducing ...

ATP synthase is a universal molecular machine for energy conversion. By coupling to cellular respiration in mitochondria, it catalyzes conversion of chemical energy of cells. Mitochondrial ATP ...

Researchers at the University of Cologne have identified the key mitochondrial protein AIFM1 as a central coordinator of ...

Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to ...

F1FO-ATP synthase is critical for mitochondrial functions. The deregulation of this enzyme results in dampened mitochondrial oxidative phosphorylation (OXPHOS) and activated mitochondrial ...

The experimental drug J147 is something of a modern elixir of life; it’s been shown to treat Alzheimer’s disease and reverse aging in mice and is almost ready for clinical trials in humans. Now, Salk ...

Background. Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease. Many of these diseases are tied to a deficiency in ATP synthase thought to be triggered ...

atp synthase; News on atp synthase. Date. 6 hours 12 hours 1 day 3 days all. Rank. Last day 1 week 1 month all. ... resulted in a promising study toward a better understanding of mitochondrial ...

P5CS-containing mitochondria showed higher membrane potential, suggesting that they engage in reductive metabolism for proline and ornithine synthesis, while ATP synthase-enriched mitochondria are ...

Through genome sequencing, researchers found a mutation in a particular enzyme known as mitochondrial ATP synthase. Cells need this enzyme to generate ATP, a molecule that is essential to storing ...

Proteomics in Neurodegenerative Diseases: A Focus on Mitochondrial Dysfunction & Oxidative Stress In the last 10 years, proteomic approaches have been largely applied in order to identify which ...