Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

The subsequent breakdown of the nuclear envelope terminates prophase and initiates prometaphase, during which the chromosomes become attached to and positioned on the mitotic spindle as it forms.

Chemotherapy often includes drugs that target the cancer cells’ mitotic spindle — a flexible microscopic scaffolding that helps pull identical copies of chromosomes apart during cell division ...

During mitosis, the spindle fibers are called the mitotic spindle. Meanwhile, during meiosis, the spindle fibers are referred to as the meiotic spindle. At the beginning of nuclear division ...

A large structure called the mitotic spindle also forms from long proteins called microtubules on each side, or pole, of the cell. During prometaphase, the nuclear envelope that encloses the ...

This could include studies focusing on different parts of the mitotic spindle, i.e. spindle microtubules, centrosomes and kinetochores, and various key proteins playing important roles in the ...