the major histocompatibility complex (MHC) of the NOD mouse (designated H2 g7) contributed the main component of susceptibility, and that the MHC class II I-Aβ chain showed the same 'diabetogenic ...
Shi and Beutler and UTSW colleagues created mouse models with ... type" form of the gene. H2-Aa is responsible for producing part of an immune protein called MHC class II, which helps the immune ...