Full-year results and business updateClinical proof of principle obtained in Phase I adjuvant head and neck cancer trial with individualized ...

Embryo transfer: Implant the injected eggs into the oviduct of a pseudopregnant female mouse. Genotyping: Analyze offspring ...

To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...

Some cre-transgenic mouse strains exhibit clear phenotypic ... It remains unclear whether this is due to high expression of Cre, transgene insertion effects or a combination of both.

Mus musculus House mouse Commonly used to study genetic principles ... knock-in mice are produced by inserting a transgene into an exact location where it is overexpressed. Over the years, more ...