Figure 3: Actin-binding properties of wild-type and mutant D. discoideum (Dd) myosin motor domain (MD). Figure 4: Mutations in the activation loop of myosin suppress actin activation, whereas in ...

This is the first time we were able to structurally visualize the weak binding states of actin and myosin, not interpolated from crystal structures, and not interpolated from biophysical methods ...

A cartoon showing the asymmetry in the weak binding between myosin and actin that biases the direction of their dissociation. Credit: Osaka University Researchers love to use cartoons to demonstrate ...

Finally, the scientists propose that nebulin regulates the binding of actin and myosin, and hence muscle contraction, by interacting with another protein called troponin. Experiments were done on ...

The images also give clues into how myosin moves along actin. The binding of ATP forces a rotation within the myosin molecule that reduces the number of bonds between it and actin. This weakly ...

Blue light exposure then induces the translocation of SspB-PP1BD from the cytoplasm to the membrane through binding to iLID ... and consequently, actin and myosin-mediated contractile force ...

Stossel and Hartwig decided to purify myosin from white blood cells as a way to find the ... A high molecular weight polymer they would soon identify as the first actin-binding protein, later called ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...

Boron, though required only in minimal amounts, is vital for plant development. It strengthens cell walls and supports the ...