A parent with NF1 has a 50% chance of passing the abnormal gene copy to a child. A child who inherits the altered gene will also have the disorder. It’s important to determine whether the disorder is ...

As a result, it is often impossible to make a definitive diagnosis of NF1 in a young child with only multiple café-au-lait spots. Also, there are other conditions, for example a rare disorder called ...

They found that changes causing a loss of NF1 gene function were not limited to tumours and skin changes but instead can be found throughout other tissues of the child with NF-1 as well.

They found that changes causing a loss of NF1 gene function were not limited to tumors and skin changes but instead can be found throughout other tissues of the child with NF-1 as well.

Professor Thomas Jacques, co-senior author from UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital, said, "NF-1 can have many different impacts on a person's life.

Genetic changes alone don’t fully explain tumor growth in NF-1, pointing to other contributing factors. This insight may ...

Sumrall, MD The FDA has approved an oral, small molecule MEK inhibitor for adult and pediatric patients 2 years of age and older with neurofibromatosis type 1 who have symptomatic plexiform ...

Young Damir Ortiz Ramírez from Cuba, diagnosed with neurofibromatosis type 1, a plexiform neurofibroma in his right eye, and ...