Inactivating germ line mutations in the neurofibromatosis type 1 (NF1) gene are responsible for the many manifestations of this disease that range from intellectual deficits, to autism, to bone ...

Genetic testing for people with type of NF, while possible, can be more complex than for individuals who do not have this form of the disorder. In cases where a child’s NF1 is determined to be the ...

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) ...

Universiti Kebangsaan Malaysia (UKM) Neurosurgeon Prof Kamalanathan Palaniandy explains that Neurofibromatosis type 1 (NF1) is the most common among the three variants of Neurofibromatosis.

Von Recklinghausen disease (VRD) is also called neurofibromatosis type 1 (NF1). It is a genetic disorder in which the growth of nervous tissue is altered, producing tumors related to the nerve sheath.

Affected children are born with café-au-lait spots and sometimes Lisch nodules. During adolescence and young adulthood, more ...

A multicenter collaboration has identified a potential new treatment for an aggressive sarcoma arising in the nerves. The ...

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Neurofibromatosis type I is often associated with learning disabilities. Recent work shows that lack of neurofibromin impairs memory because overactive ERK signaling in hippocampal interneurons ...

In a recent blog, I discussed the change in nomenclature for the conditions formerly known as Neurofibromatosis type 2 (NF2) and schwannomatosis. This change was based on the results of an ...