They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But as they age, they accumulate more and more DNA damage. Until now, it has ...

The researchers then collected oocytes from these pups when they reached puberty at ... To understand the effect of ovarian aging on these long-lived proteins, the researchers tested their abundance ...

It was a finding too striking to be trusted. Elvan Böke, a molecular biologist at the Center for Genomic Regulation in Spain, was studying how immature egg cells in animals, called oocytes, stay ...

Aging egg cells can be rejuvenated when placed inside young follicles, a new study of mouse cells suggests. The study could ...

Nonetheless, Slater's conclusion that the poly(A) tails were elongated by polyadenylation in the cytoplasm of the oocytes after fertilization was still valid and intriguing and set further ...

A study by Zhang et al. now identifies aging-related decline of the polyamine spermidine as a crucial bottleneck for oocyte quality. Supplementation with spermidine rejuvenates oocytes in vitro ...

“We found that DNA repair slows down in aged oocytes,” says Schuh ... part can be repaired using an intact DNA strand as a blueprint. But it is not only aging egg cells that are affected by cohesion ...