In humans and mammals, almost 80% of the nitrogen excreted is in the form of urea, which is produced ... In babies, elevated levels of orotic acid in the urine may be an indicator of OTC deficiency.

Carbamoyl phosphate synthetase I (CPS1) deficiency (CPS1D), a rare type of urea cycle disorder (UCD ... and arginase deficiency by amino acid profiles. Orotic acid in urine can help distinguish ...

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.