Multiple myeloma causes lytic or osteolytic lesions, which are areas of damage caused by cancerous plasma cells blocking normal bone growth. While painful, they can be managed. Multiple myeloma is ...

Some people may also refer to lytic lesions as bone or osteolytic lesions. The term refers to spots of bone damage that can occur with conditions that affect bone. For example, evidence notes that ...

Patients were considered to have bone involvement based on the presence of one or more osteolytic lesions and/or osteoporosis on the skeletal survey, according to the CRAB criteria. 6 The presence ...

Patients presenting with underlying osteolytic lesions and/or paramedullary lesions, arising from bone, and/or extra-medullary disease, arising in soft tissues, were excluded from the study as ...

We subjected purified plasma cells from the bone marrow of patients with newly ... analyses to identify molecular determinants of osteolytic lesions. We studied 45 control subjects, 36 patients ...

Identifying osteoblastic lesions clearly versus the more ominous ... This metastatic spread to the spine can be characterized as osteolytic (bone destructive), osteoblastic (bone constructive ...

New innovative local treatment for osteolytic bone disease in multiple myeloma Date: January 14, 2025 Source: Vrije Universiteit Brussel Summary: A team of researchers has developed a new ...

Bone marrow analysis showed normocellular marrow ... there is a risk of progression to osteolytic lesions, making careful follow-up particularly important. Although this rare form of multiple myeloma ...

These lesions cause severe pain and fractures ... Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma, Journal ...

Also known as bone lesions or osteolytic lesions, lytic lesions are spots of bone damage that result from cancerous plasma cells building up in your bone marrow. Your bones can't break down and ...

leading to debilitating bone lesions in 80% of patients. These lesions cause severe pain and fractures that often fail to heal, and within, a vicious cycle takes place that supports tumor survival ...

BoXer releases this 'payload' locally at the site of bone lesions, offering a dual therapeutic ... collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in ...