Mitochondria are the body's "energy factories," and their proper function is essential for life. Inside mitochondria, a set ...

The mitochondrion is the major cellular site of energy production and respiration involving the process of oxidative phosphorylation. Mitochondrial defects have been implicated in the pathogenesis ...

Study results advance understanding of how human cells evolved and could help point to new solutions for patients with rare genetic diseases.

Oxidative phosphorylation drives the synthesis of ATP and takes place through a series of reactions mediated by complexes I, II, III, IV, and V, which are integral to the inner mitochondrial membrane.

Although the data from the study participants indicated that the TP53 mutations associated with the Li–Fraumeni syndrome can promote oxidative metabolism by means of increased mitochondrial ...

Harrington’s study, “Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells,” was recently published in the journal Cell Reports. Harrington ...

Aerobic glycolysis is critical for tumor growth and metastasis. Previously, we have found that the overexpression of the inhibitor of growth 5 (ING5) inhibits lung cancer aggressiveness and ...