Hosted on MSN2mon
A potential pathway may guide new therapies for inflammatory bowel disease and other inflammatory diseases
"Our results show that BB1 prevented the TNF-α increase in intestinal tight junction permeability via a toll-like receptor (TLR)-2 signal transduction pathway inhibition of NF-kB p50/p65 ...
Nature9mon
New regulators of NF-κB in inflammation
When CYLD and BCL-3 are co-expressed, p50 or p52 homodimers are displaced ... p100 can regulate a fraction of canonical, p65-containing NF-κB dimers through pathways that signal through IKKα ...
Medscape9d
Salicylate-Based Anti-Inflammatory Drugs Inhibit the Early Lesion of Diabetic Retinopathy
[41] Since EMSA and transcription factor array data showed that the oral administration of aspirin to diabetic rats resulted in DNA-binding affinity changes for NF-κB (p50/p65 and p65/p65), we ...
Inquirer Business on MSN1d
MPIC to sell 20% stake in tollways business
Metro Pacific Investments Corp. (MPIC) is selling up to 20 percent of its stake in its tollways business to reduce debt and ...
GMA Network on MSN12d
NLEX toll hike strains consumers, suppliers as vegetable prices climb
Consumers and vegetable suppliers in Metro Manila face a heavy burden due to the NLEX toll hike as prices are affected. In ...