[78] Several potent non-selective tyrosine kinase inhibitors that interrupt both VEGF and PDGF signaling have been approved for cancer therapy: imatinib, sorafenib, pazopanib, sunitinib ...

Brain tumours remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...

PDGF and its receptors are implicated in tumorigenesis and angiogenesis, prompting Sebti and colleagues to design a synthetic molecule, called GFB-111, that binds to PDGF. Their new molecule has ...

Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...

This article reviews previous experiences and current and future development strategies of sorafenib in breast cancer ... 2 and 3, PDGF receptors α and β, RET, Flt3, c-KIT and the RAF kinase ...

This innovative hydrogel has the potential to improve the efficacy of cancer treatment and wound ... wound healing with growth factors like PDGF-BB. Additionally, the hydrogel proved effective ...