The phosphoinositide 3-kinase (PI3K) pathway is a crucial ... Inhibitors that target key components of this pathway, including PI3K, AKT and mammalian target of rapamycin (mTOR), are being ...

The frequency of high blood glucose among patients receiving PI3K/Akt inhibitors to treat breast cancer has some oncologists ...

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT ... RAF kinase-driven ERK activation. The combination of Hsp90 inhibitors with RAF or ...

Creative Proteomics announced the launch of a Glycolysis Pathway Analysis platform that incorporates LC-MS/MS metabolomics, stable isotope tracing, and computational flux modeling for a complete ...

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...